RESULTS
Maximum increases in insulin concentration after consumption of the CAC meal than after that of the BAB meal. The maximum increases in insulin concentration and iAUC for serum insulin after the CAB meal were in between but closer to those with the CAC meal than with the BAB meal. The maximum increases in insulin concentration and iAUC for serum insulin after the CAB meal were 15% and 17% lower, respec- tively, than after the BAB meal. The maximum increases in insulin concentration and iAUC for serum insulin after the CAC meal were 24% (P = 0.24) and 18% (P = 0.52) lower, respec- tively, than after the CAB meal. The maximum increases in C-peptide concentration and iAUC for C-peptide were not sig- nificantly different between the 3 meals (Table 2). There was no significant difference (P = 0.1) in EE (Figure 4) or in the respi- ratory quotient between the 3 meals (Table 2).
The analysis showed that the significant heterogeneity observed between the 3 meals in the whole group came predom- inantly from the subjects with a BMI > 26.3. In addition to these results, subjects with a BMI > 26.3 showed significant heterogeneity in maximum C-peptide, iAUC C-peptide, iAUC C-peptide/insulin quotient, and net AUC EE. Postestimation analysis showed a higher C- peptide/insulin quotient, and a lower net EE after the CAB meal and the CAC meal than after the BAB meal. The maximal change in C-peptide was smaller with the CAC meal than with the CAB and the BAB meals, and iAUC C-peptide was lower after the CAC meal than after the BAB meal (P = 0.015).