Phosphorylation of PFK regulates the compartmentalization of the enzyme to provide energy to the cellular component by forming a complex with actin (Cai et al., 1997 and Kuo et al., 1986). Protein phosphorylation regulates postmortem glycolysis by regulating the activity or stability of glycolytic enzymes (Huang et al., 2011). Shen and Du (2005) report that the glycolysis and pH decline are indirectly affected by the phosphorylation status of AMP-activated protein kinase (AMPK) in postmortem muscle. In brief, it can be concluded that protein phosphorylation regulates the rate and extent of pH decline in postmortem muscle by controlling the glycolysis reactions.