Communication
has been incorporated in some established applications such as
medical implants and drug-delivery systems [13–15]. Besides,
it is suitable for use in resorbent sutures, or other production
of biocompatible/bioabsorbable medical devices which could
be readily adopted in the drug release and as implants for
orthopedic surgery or blood vessels [7, 16].
Meanwhile, nanotechnology applied to biological
problems represents an emerging field [17–19]. Nanoparticles
in drug delivery systems, due to their diminutive size,
can penetrate across barriers through small capillaries into
individual cells to allow efficient drug accumulation at
the targeted locations in the body [20, 21]. Titanium
dioxide (TiO2), especially TiO2 nanoparticles, has been
applied in biomedical and bioengineering fields due to its
oxidizing and biocompatible properties, chemical inertness
and photoactivity [22–24].