tions promote the rapid loss of repellent from the
surface of the skin.19 In our study, a formulation containing
23.8 percent DEET provided an average of
five hours of complete protection against A. aegypti
bites after a single application. Depending on the formulation
and concentration tested, DEET-based repellents
have been shown in other studies to provide
complete protection against arthropod bites for as
long as 12 hours, even under harsh climatic conditions.20,21
The most recent addition to the synthetic insect
repellents on the market in the United States is
IR3535,22 which is classified by the Environmental
Protection Agency as a biopesticide because of its
structural similarity to the amino acid alanine. This
repellent has been used in Europe for more than 20
years and was approved for use in the United States
in 1999. In our tests, this repellent fared poorly, yielding
a mean complete-protection time that was one
quarter that of the lowest-concentration DEET product
we tested (22.9 vs. 88.4 minutes).
tions promote the rapid loss of repellent from thesurface of the skin.19 In our study, a formulation containing23.8 percent DEET provided an average offive hours of complete protection against A. aegyptibites after a single application. Depending on the formulationand concentration tested, DEET-based repellentshave been shown in other studies to providecomplete protection against arthropod bites for aslong as 12 hours, even under harsh climatic conditions.20,21The most recent addition to the synthetic insectrepellents on the market in the United States isIR3535,22 which is classified by the EnvironmentalProtection Agency as a biopesticide because of itsstructural similarity to the amino acid alanine. Thisrepellent has been used in Europe for more than 20years and was approved for use in the United Statesin 1999. In our tests, this repellent fared poorly, yieldinga mean complete-protection time that was onequarter that of the lowest-concentration DEET productwe tested (22.9 vs. 88.4 minutes).
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