The present study was designed to evaluate the in vitro antifungal susceptibility of
M. pachydermatis strains from dogs with or without skin lesions to KTZ, ITZ, miconazole
(MICO), fluconazole (FLZ), posaconazole (POS), voriconazole (VOR) and terbinafine (TER)
using the Clinical and Laboratory Standards Institute reference Broth Microdilution
Method (CLSI M27-A2). The association between the susceptibility to antifungal
compounds and the origin of M. pachydermatis, from skin with or without lesions has
been also assessed. A total of 62 M. pachydermatis strains from healthy dogs (i.e., Group
A = 30) or with skin lesions (i.e., Group B = 32) were tested. ITZ, KTZ and POS showed the
highest activity against M. pachydermatis strains, whereas MICO TER and FLZ the lowest. A
higher number of Malassezia resistant strains were registered among isolates from Group B
than those from Group A.
The present study was designed to evaluate the in vitro antifungal susceptibility of
M. pachydermatis strains from dogs with or without skin lesions to KTZ, ITZ, miconazole
(MICO), fluconazole (FLZ), posaconazole (POS), voriconazole (VOR) and terbinafine (TER)
using the Clinical and Laboratory Standards Institute reference Broth Microdilution
Method (CLSI M27-A2). The association between the susceptibility to antifungal
compounds and the origin of M. pachydermatis, from skin with or without lesions has
been also assessed. A total of 62 M. pachydermatis strains from healthy dogs (i.e., Group
A = 30) or with skin lesions (i.e., Group B = 32) were tested. ITZ, KTZ and POS showed the
highest activity against M. pachydermatis strains, whereas MICO TER and FLZ the lowest. A
higher number of Malassezia resistant strains were registered among isolates from Group B
than those from Group A.
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