In total, 5 studies met the criteria and were included in the systematic review. Three studies assessed the effectiveness of honey against
other products including golden syrup, lignocaine and saline and two studies assessed the effectiveness of honey against standard treatment regimes.
Four out of the five studies demonstrated significant reduction in the mucositis levels and one study reported that honey had no statistical association
with less severe mucositis. Methodologically the quality of most studies was moderate due to the small sample size, which might impact upon the
significance of the findings.