parallels that of the control group. Rats fed with EOC alone showed a slight reduction in both left and
right hind paw swelling from day 17 to day 20 (Fig. 3a, b).
The formic acid-formalin fixed hind foot pads were sectioned at the metatarsus region for histological
evaluation. The hind paw is made up of the foot pads and five digits which consists of elongated
metatarsal bones and phalanges. The total histopathology scores of the left hind paws from rats in the
GLU + EOC group were significantly lower than that of control rats (p < 0.05) (Fig. 4a). A similar trend
of the histopathology score of the right hind paws was observed, though this was not statistically