All patients received 2 capsules (250 mg each) of curcuminoids
daily for 12 months. Curcuminoids capsules, kindly donated from The
Government Pharmaceutical Organization, Bangkok, Thailand, are
comprised of curcumin, demethoxycurcumin, and bisdemethoxycurcumin
in the ratio of 1:0.3:0.1. Blood samples were collected every 2
months during treatment and 3 months after withdrawal.