Calcium and phosphorus bioavailability from different milk-based (whole milk, skimmed milk and soya milk)
fruit beverages as affected by thermal treatment (TT) and high-pressure processing (HPP) was determined by
means of the paired in vitro gastrointestinal digestion (solubility method)/Caco-2 cell model. Ca
bioaccessibility was significantly higher in HPP (98.4%± 1.6%) versus TT (91.3%± 1.9%), but Ca bioavailability
was equal in all different matrixes independently of the processing treatment used. HPP samples improved P
bioaccessibility (98.7%± 2.5% versus 87.3%± 2.2%) and P bioavailability by Caco-2 cells versus TT samples—
soya milk- and wholemilk-based beverages being the samples with the highest bioavailability values (56.8%±1.3%
and 40.1%±9.9% versus 15.0%±2.1% and 16.8%±2.8%, respectively). Therefore, HPP improves Ca and P
bioaccessibility, and P bioavailability versus TT samples, and can be used as an alternative to TT in the manufacture
of functional foods with improved nutritional value and health benefits