Increase in reaction time caused by application of coniine in 10 mg/kg dose was not changed by the concomitant administra tion of morphine in increasing doses.
Coniine in 20 mg/kg dose increased reaction time in different doses of morphine application.
Morphine at 5 mg/kg dose avoided animals to show any response until cut-off time so cut-off time (P < 0.01; Fig. 3)