Polyamines (PAs) are low molecular weight organic cations
often capable to mimic the action of divalent cations both in vitro
and in vivo (Tabor & Tabor, 1984). The effects of the different PAs,
compared to calcium ions, were recently studied by using layers
of phosphatidic acids as biological systems to understand the
stabilization mechanisms of cell membranes (Rudolphi-Skorska,
Zembala, & Filek, 2014). The very low toxicity of PAs, attested by an
acute oral toxicity of 2000 and 600 mg/kg in rats, for putrescine