Many donor-specific risk factors for DGF in renal transplantation
have been identified, including both immunologic
(e.g. absence of T-cell antibody induction therapy, female
donor gender) and nonimmunologic (donor age, weight,
prolonged cold/warm ischemia time) origin (13,48,54–56).
A donor scoring system based on a small cohort of patients
was developed to quantify some of these risks
to determine early (day 30) graft function and assist in
“marginal” donor allocation (57). Other investigators developed
a nomogram that quantified a large number of risk
factors, each of which demonstrated predictive discrimination
andwere independently correlated with DGF (58). This
nomogram was further refined in 2010 with more recent
data reported to the United Network for Organ Sharing
(UNOS)/Organ Procurement and Transplantation Network
(OPTN)(59).
Composite recipient risk
Distinct patient characteristics of the recipient place him