FIG. 2.
Schematic view of the mode of action of Mig1 and its regulation. In the presence of glucose, Mig1 is found in the nucleus, where it represses the transcription of genes encoding activators such as GAL4 and MAL63 and of genes whose products are implicated in the metabolism of alternative carbon sources. Glucose removal causes both phosphorylation of Mig1, depending on the Snf1 complex, and its translocation to the cytoplasm. For details, see the text.