3.2. In vitro cytotoxicity
Acrolein as positive control substance (data not shown) as well
as TPM and GVP of the reference cigarette 2R4F produced cytotoxicity
results consistent with historical data from the laboratory.
Cytotoxicity results on a per cigarette basis are given in the
Appendix in Table C. There were no significant differences between
the mean 1/EC50 values for Mixes A, B and C, compared with the
appropriate control cigarette data, for both the TPM and the GVP.