In conclusion, the results of the present study indicate that the optimal dietary M:M+C is increased during Immune system stimulation in growing pigs. This may be due to the inherent increased need for Methionine as a methyl donor and an antioxidant in the Methionine sulfoxide reductase system or due to the increased transsulfuration of Methionine to Cystein for the synthesis of compounds involved in the immune response, such as glutathione and acute phase proteins. The current findings support the development of optimal dietary Amino Acid profiles for diseased pigs. However, further research should be conducted with dietary M:M+C that exceed 0.62 to determine the optimal ratio in Immune system stimulation growing pigs because the response to increasing M:M+C was maintained at the greatest dietary M:M+C that was evaluated in the current study.
Moreover, the impact of different types of disease or Immune system stimulation on Met and Cys requirements may be explored