3. Results and Discussion
3.1. A Preliminary Wound Healing Comparison Study on RB Maltodextrin with the Addition of 100 ppm of Various Additives
In vitro wound healing process starts with the spreading of individual cells at the wound edge and the synthesis of matrix fibrils (e.g., fibronectin), followed by cell migration (translocation) along the fibronectin and cell proliferation process [23]. Table 1 shows the results of a preliminary study of in vitro wound healing on RB maltodextrin. In this study, the NIH 3T3 cells were seeded in six-well culture plates to test the wound healing effect of RB maltodextrin with and without 100 ppm of various additives. Overall, this study consisted of three parameters with the aims to examine the wound healing effect of (a) different concentration of additives choice; (b) different concentration of RB maltodextrin; and (c) different DE grades of RB maltodextrin. These factors were studied to identify the optimum condition of RB maltodextrin to assist the wound healing of NIH 3T3 cells.