In the present study, we have evaluated the virus
inhibitory potential of methanol and aqueous extract by
means of in vitro system. The different exposure studies
revealed that the anti-influenza activity of aqueous and
methanol extract was higher in simultaneous and postpenetration
exposure experiment than pre-penetration
exposure experiment. From this study it appears that during
simultaneous exposure, J. curcas extracts probably exert
their effect by preventing viral adsorption onto the cells
since viral hemagglutination was inhibited, which is mediated
by the sialic acid-specific hemagglutinin protein.