ABSTRACT Objective: Prolonged use of endotracheal (ET) tube has been recognized as a major threat for developing
Ventilator associated Pneumonia (VAP) particularly by Gram negative organisms. So the purpose of the study
was to determine the organisms causing VAP and to study their antimicrobial susceptibility pattern. Materials and Method: This ret-
rospective observational study was conducted over a period of 9 months from January -September 2012 in microbiology department,
G.G.H. hospital, Jamnagar during which total 82 ET tube samples were received. Identification of bacteria was done by various
biochemical tests. antibiotic sensitivity of isolate was done by Kirby-Baur method. Result: 24 (72.73%) isolates are gram nega-
tive bacteria & 9 (27.27%) infections are due to gram positive bacteria. Acinetobacter baumannii (18 samples; 54.5%) was the
most common organism isolated, which was resistance to commonly used antibiotics. Conclusion: There is a need to improve the
effectiveness of integrated infection control programs to control and manage nosocomial infections caused by highly resistant
organisms.