Concentrated hydrochloric acid is extremely corrosive.
Concentrated ammonia solution is harmful to contact with
skin and eyes and can release ammonia vapors that are severely
irritating to the eyes and to the respiratory tract. TiCl4 can
cause severe skin burns and eye damage. For this reason,
laboratory coats, gloves, and goggles should be worn and the
reactions must be performed under a fume hood with adequate
ventilation. Dropping TiCl4 into concentrated HCl and adding
ammonia to the yeast−TiCl4 solution are highly exothermic
processes, resulting in the development of toxic fumes.
Laboratory tutors and teachers should carefully assist students
during these two operations