3.5.2.2. Bacterial biofilms and resistance
In practice, most bacteria are associated with surfaces and grow as biofilm rather than as planktonic cells. Bacterial biofilms have been consistently described as being moreresistant to biocides and antibiotics than planktonic cells . The reasons for this decrease in susceptibility is a biofilm-associated phenotype , including decreased metabolism, quiescence, reduced penetration due to the extracellular polymeric matrix , enzymatic inactivation of biocides , and the induction of multi-drug resistant operons and efflux pumps .
Although bacteria within biofilms are undeniably more resistant to biocides and antibiotics, the link between the uses of biocides against bacterial biofilm and potential emergingantibiotic resistance is not straightforward. In a recent study investigating the use of chloraminated drinking water against Ps. aeruginosa biofilm, there was no evidence that the use of chloramine induced an increase in antibiotic resistance .
3.5.2.2. Bacterial biofilms and resistanceIn practice, most bacteria are associated with surfaces and grow as biofilm rather than as planktonic cells. Bacterial biofilms have been consistently described as being moreresistant to biocides and antibiotics than planktonic cells . The reasons for this decrease in susceptibility is a biofilm-associated phenotype , including decreased metabolism, quiescence, reduced penetration due to the extracellular polymeric matrix , enzymatic inactivation of biocides , and the induction of multi-drug resistant operons and efflux pumps .Although bacteria within biofilms are undeniably more resistant to biocides and antibiotics, the link between the uses of biocides against bacterial biofilm and potential emergingantibiotic resistance is not straightforward. In a recent study investigating the use of chloraminated drinking water against Ps. aeruginosa biofilm, there was no evidence that the use of chloramine induced an increase in antibiotic resistance .
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