lymphadenectomy
had no impact on the receipt of chemotherapy for both low and
high-risk patients, high-risk women who underwent lymphadenectomy
were less likely to receive chemotherapy for N3 months. Further,
one would expect that approximately 30% of the patients in our series
would have been up staged had they undergone lymphadenectomy
.
Women with low-risk tumors are unlikely to derive benefit from
chemotherapy . Current recommendations by the National Comprehensive
Cancer Center (NCCN) recommend observation for patients
with stage IA/IB grade 1 tumors and observation or chemotherapy for
grade 2 neoplasms . Consistent with these data, we found no improvement
in survival for low-risk patients treatedwith chemotherapy.
We did however note that the use of chemotherapy was not only