In total, out of 55 newborns with Medi-terranean mutation, 42 subjects (76.4%) were male and 13 (23.6%) were female; out of 3 neonates with Chatham mutation, 15 cases (16%) were male and 10 (40%) were female (P=0.091), and out of 20 patients with Cosenza negative, 16 (80%) were male and 40 (20%) were female. The mean bilirubin levels and hospital stay showed no significant difference in icteric group for different types of mutation (Table 2).