The cell-to-cell signaling mechanism, known as quorumsensing,
exerted by bacteria to control their density of
population growth and biofilm formation, involves the
excretion of so-called quorum-sensing compounds. The best
studied are the acyl homoserine lactones (AHLs), with
compounds, including N-3-oxohexanoyl-l-homoserine lactone significant discovery is the isolation of the cytotoxic macrolide palmerolide A (13; Scheme 3) from an Antarctic tunicate, with total synthesis leading to a revision of the
original structure
The cell-to-cell signaling mechanism, known as quorumsensing,
exerted by bacteria to control their density of
population growth and biofilm formation, involves the
excretion of so-called quorum-sensing compounds. The best
studied are the acyl homoserine lactones (AHLs), with
compounds, including N-3-oxohexanoyl-l-homoserine lactone significant discovery is the isolation of the cytotoxic macrolide palmerolide A (13; Scheme 3) from an Antarctic tunicate, with total synthesis leading to a revision of the
original structure
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