both met the MSIS criteria on the basis of elevated in flammatory markers,
synovial fluid leukocytosis with elevated polymorphonuclear percentage
in addition to a single microorganism isolated from periprosthetic specimens.
The isolation of the same microorganism(s) in 2 or more specimens was the only diagnostic
criterion in 18 PJI subjects (10%), 9 of which (50%) were associated with P. acnes. The
demographic, clinical, and laboratory characteristics of this cohort are outlined in Table 2.
A median of 4 periprosthetic tissue and/or fluid samples was collected per subject;
subjects with PJI had a higher number of samples submitted for culture compared to AF
subjects (median 5 [range, 1–13] versus 3.5 [range, 1–10] specimens, respectively;
P b 0.0001). Preoperative synovial aspiration was performed in 118 (47%) subjects, including
53% and 30% of PJI and AF subjects, respectively (P = 0.001). Implant vortexing/sonication
culture was performed in 61 (23%) subjects, including 25% and 9% of the PJI and AF
subjects, respectively (P = 0.3).
both met the MSIS criteria on the basis of elevated in flammatory markers, synovial fluid leukocytosis with elevated polymorphonuclear percentagein addition to a single microorganism isolated from periprosthetic specimens.The isolation of the same microorganism(s) in 2 or more specimens was the only diagnosticcriterion in 18 PJI subjects (10%), 9 of which (50%) were associated with P. acnes. Thedemographic, clinical, and laboratory characteristics of this cohort are outlined in Table 2.A median of 4 periprosthetic tissue and/or fluid samples was collected per subject;subjects with PJI had a higher number of samples submitted for culture compared to AFsubjects (median 5 [range, 1–13] versus 3.5 [range, 1–10] specimens, respectively;P b 0.0001). Preoperative synovial aspiration was performed in 118 (47%) subjects, including53% and 30% of PJI and AF subjects, respectively (P = 0.001). Implant vortexing/sonicationculture was performed in 61 (23%) subjects, including 25% and 9% of the PJI and AFsubjects, respectively (P = 0.3).
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