The electrochemical behaviour of the three target molecules, AA, LD and UA was studied on non-modified CSPE as well as on MWCNT, GNRox and GNRred modified electrodes using These excellent results in terms of electroanalytical performance could be interpreted at the light of the characterization findings obtained on the GNRred surfaces (see Table 1). The higher content of defects and edge sites, showed by Raman spectroscopy, as well as the removal of the oxygen functionalities that significantly decreases, showed by XPS, resulted in drastically lowered the potential values for GNRred.