In the clinical care of renal patients, nutritional therapy is very important. Since the early stages of CKD, “ normalization” of dietary intake of energy, protein, sodium and phosphorus play a crucial role for the renal protection. In more advances stages of CKD, protein-restricted diets are able to prevent or ameliorate uremic symptoms or complications, such as metabolic acidosis, mineral and bone disorders, insulin resistance, proteinuria, hypertension and fluid retention, and to maintain nutritional status [1-3]. Evidence exists that protein-restricted diets can delay the need of dialysis [4] , whereas the effect of slowing the rate of GFR decline is not so evident [5].