We did not observed statistically significant variations regarding HPV DNA types 16–18 in cancer over the decades, being HPV16 the most frequent type, in all decades (58.2%), of all viruses detected followed by HPV18 (9.2%).
We, as other did previously, also observed a lower age at diagnosis of cervical cancer attributable to HPV16, HPV18 and HPV45 [14], [15] and [16]. This finding might be important regarding the beginning of screening of HPV vaccinated cohorts, as HPV45 type is not included in quadrivalent vaccine.