TABLE 2. PROTEINS IDENTIFIED BY MALDI MASS SPECTROMETRIC ANALYSIS IN HUMAN SINONASAL
MUCOSA GROUPED BY PROTEIN ORIGIN AND LISTED IN ORDER OF SIGNIFICANCE BY NAME AND
SWISSPROT ACCESSION NUMBER
SwissProt % Average Ratio
Human Protein Identified Accession Coverage Difference* Protein Origin
Eosinophil lysophospholipase Q05315 55 18.13 Vascular
Endoplasmin P14625 33 8.33 Functional-regulatory
Actin,cytoplasmic 2 P63261 43 7.63 Cytoskeletal
Glyceraldehyde-3-phosphate dehydrogenase P04406 38 6.20 Functional-regulatory
Protein SI00-A8 P05109 61 5.63 Functional-regulatory
Ubiquitin carboxyl-terminal hydrolase 5 P45974 48 4.53 Functional-regulatory
RHO-GDP dissociation inhibitor 2 P52566 67 2.80 Functional-regulatory
Apolipoprotein A-1 P02647 59 1.73 Vascular
Actin,cytoplasmic 1 P60709 38 -5.27 Cytoskeletal
Catalase P04040 34 -5.87 Functional-regulatory
Annexin A1 P04083 43 -6.27 Functional-regulatory
Carbonic anhydrase P00915 58 -6.59 Functional-regulatory
Keratin type 11-8 P05787 70 -6.73 Cytoskeletal
Retinal dehydrogenase P00352 42 -9.07 Functional-regulatory
Phosphatidylethanolamine-binding protein I P30086 74 -9.90 Functional-regulatory
MALDI — matrix-assisted laser desorption and ionization.
*Positive ratio values indicate increased abundance in samples from patients with CRSwNP compared to controls.and negative ratio values indicate decreased abundance in samples from patients with CRSwNP compared to controls.