Of these, trisomy 18 is associated with more severe IUGR compared with trisomy 21 or 13. Trisomy 16 is known to be a lethal chromosomal abnormality in the nonmosaic state; however, in the presence of placenta mosaicism, trisomy 16 can result in IUGR.
Of these, trisomy 18 is associated with more severe IUGR compared with trisomy 21 or 13. Trisomy 16 is known to be a lethal chromosomal abnormality in the nonmosaic state; however, in the presence of placenta mosaicism, trisomy 16 can result in IUGR.