hepatitis B and hepatitis C are a concern because of their association with cirrhosis and liver cancer. Although exact numbers are not known,it is estimated that about 200 million people worldwide have the hepatitis C virus (HCV), making this type of hepatitis the most common type. Currently there is no vaccine for HCV. Therefore it is expected that the cases of HCV will rise over the next several decades as a result of increasing illicit drug use. this increase will require major increase in transplantations lead to many more deaths.