The early diagnosis of somaclonal variation has been tested
using DNA markers whereas James et al. [7] stated that the
source of this variation may derive from variation pre-existing
in the mother plant or it may be induced in vitro. Many factors
are known to influence in vitro induced variation, however, it
has been proposed that hypo- or hypermethylation of DNA,
which may trigger genome-wide changes, may be the underlying
cause.