In this experiment, 30 laboratory albino mice were fasted for 8 hours but given water ad- libitum and were divided into five groups of 6 mice each. The mice in group 1 (negative control group) received 0.5ml of normal saline orally while those in groups 2, 3, 4 and 5 were treated with the ethanolic fruit extract of Psidium guajava at the doses of 5000, 10000, 15000 and
20000mg/Kg respectively prepared from a stock
of 400 mg/ml of extract. The number of dead mice per group within 24 hours was recorded and percent mortality calculated. The signs of the toxicity were also observed and recorded.