Exposure of rats to 100 mg kg-1 bw day-1 BaP for four days increased relative liver weight by
27%, although administration of 51.4 mg kg-1 bw day-1 following partial hepatectomy did not
cause an effect. Limited evidence suggested that acute ingestion of BaP (150 mg kg-1 bw
day-1 for 4 days) does not cause adverse gastrointestinal effects in rats, although enzyme
activity was altered. It was suggested that more serious effects may occur at higher
concentrations [3]. Other studies have suggested that BaP has a fairly low toxicity in mice, it
having a LD50 of more than 1600 mg kg-1 bw [4].