Dyslipidaemia
There is substantial evidence establishing the benefits of lowering cholesterol with PAD. In the Heart Protection Study,10
PAD patients with total cholesterol >3.5 mmol/L taking simvastatin had a 17.6% reduction in cardiovascular events compared with placebo. Patients with PAD should be considered
for statin therapy that may reduce cholesterol levels, as well
as causing stabilisation and regression of existing atheromatous plaques at high doses.