Perhaps, the macronutrient composition, at
least carbohydrate and fat contents, could influence in these
differences. However, the results of Ardvidsson, Viguerie, Andersson,
Verdich, & Langin, (2004) showed that the macronutrient composition
of diets was not a major importance for the adipokine variations.
Other comparative study of low- and highcarbohydrate diets designed
for weight loss in middle-aged women has revealed that the diets are
similarly effective in reducing fat mass and leptin levels