because the human misuse antibiotics and no the rule or the legal medicine for control, such as the drugstore of some countries sale antibiotics without the control of the law because of uncontrolled sale in many low countries, where they can sale the antibiotics without a prescription from the doctors such as the drugstore in India where the people can buy the antibiotics without a prescrition, for their treatments, anti-infections and immunity so bacteria can develop and spread without control.