Data collection and analysis
Two review authors independently applied eligibility criteria, assessed risk of bias, and extracted data.We pooled dichotomous outcomes
using risk ratios (RR), and continuous outcomes using the mean difference (MD). Where possible, we pooled study results using
random-effects meta-analysis and tested statistical heterogeneity using both the Chi² test and the I² statistic test. We presented results
using forest plots with 95% confidence intervals (CI).