inflammation of the pancreas, almost always associated with acinar cell injury, is termed pancreatitis. Clinically and histologically, pancreatitis occurs as a spectrum, both in duration and severity. acute pancreatitis includes a mild, self-limited form and a more serious type, acute hemorrhagic pancreatitis, which exhibits extensive hemorrhagic necrosis of the organ. Chronic pancreatitis is the process of continuous or relapsing inflammation of the pancreas, typically causing pain and leading to irreversible morphologic damage and permanent impairment of function