For example, the segregation of donations collected
from low- and high-risk localities (e.g. lowlands and high-lands), with specific targeting of the donations from low-risk
donor groups to low risk and the most vulnerable recipients.
Routine antimalarial treatment of transfusion recipients is
also performed in some areas. Such strategies are pragmatic
approaches that are not absolute in their effectiveness, but can
help to lessen the risk of TTM in such situations. It has been
argued that many recipients in endemic areas will be immune
to the plasmodium species present where they live, and therefore
less likely to be adversely affected if they are transfused
with blood from an infected donor [9]. However, it must be
remembered that, paradoxically, many transfusions in these
countries are to children with acute severe anaemia caused by
malaria. These children are unlikely to have yet become semi-immune, and thus must be considered to be susceptible to TTM