coronary arteries irrigating the heart. With this scope, Chen et al. have created bioactive glass
nanoparticle—poly(glycerol sebacate) composites with good mechanical properties, flexibility and
biocompatibility [67]. Composites also have shown good results for wound dressing. For example
Rai et al. have synthesized bioactive glass nanoparticles-poly(3-hydroxyoctanoate) composite films
which have shown to decrease blood clotting time [68]. In addition to hemostatic properties, composite
films can help with soft tissue repair, as demonstrated by Day et al. with polyglycolic acid meshes
coated with bioactive glass micron-sized particles subcutaneously implanted in rats [69]. After
42 days, they presented complete tissue infiltration and neovascularization. Also, bioactive glass
nanoparticle–gelatin composite conduits have be shown to be good candidates to help peripheral
nerve regeneration [70]. Considering the poor regenerative capabilities of adult lung tissue, bioactive
glass particle-polymer composites have been considered for lung tissue engineering, as it could provide
a support for lung cells proliferation and adhesion. A poly(D,L-lactic acid) porous foam loaded with 5%
bioactive glass micron-sized particles, for example, has been shown to be a promising candidate [71].