Exercise also has been shown to diminish levels of
circulating advanced glycation end products (AGEs). AGEs are a
heterogeneous group of compounds created through
nonenzymatic reactions between reducing sugars and free amino
groups of proteins, lipids, or nucleic acids [11,12], Their
pathologic effects in diabetes [13] and in the development of
complications of obesity such as metabolic syndrome (MetS)
and IR [14], are related to the ability of these compounds to
promote oxidative stress and inflammation by binding with
cell surface receptors or cross-linking with body proteins,
altering their structure and function [15]. It has been
demonstrated that a program of tai chi performed twice per week for
12 mo decreased serum AGE concentrations in 60 healthy
overweight patients, aged 49 to 53 y
Exercise also has been shown to diminish levels of circulating advanced glycation end products (AGEs). AGEs are aheterogeneous group of compounds created through nonenzymatic reactions between reducing sugars and free aminogroups of proteins, lipids, or nucleic acids [11,12], Their pathologic effects in diabetes [13] and in the development ofcomplications of obesity such as metabolic syndrome (MetS)and IR [14], are related to the ability of these compounds topromote oxidative stress and inflammation by binding withcell surface receptors or cross-linking with body proteins,altering their structure and function [15]. It has been demonstrated that a program of tai chi performed twice per week for12 mo decreased serum AGE concentrations in 60 healthyoverweight patients, aged 49 to 53 y
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