Careful daily removal of the bacterial biofilm present on acrylic dentures is of paramount importance to minimize denture stomatitis and to help contribute to good oral and general health. Denture cleansing has been the subject of extensive research over the years. It was therefore surprising that little information was found on the importance of the overnight storage state of removable acrylic dentures. Stafford et al.,23 however, published a study on the effect of denture overnight drying and water immersion on candidal colonization in 1986. This study had great importance as it was the only study to evaluate the effect of overnight denture storage condition on its microbial contamination.