Cross-linking of gelatin fibres can be carried out by various chemical methods (using dialdehydes, phenolic compounds, genipin etc. [12], [13], [14] and [15]), enzymatic [16] and physical [1] and [17] means or a combination of these. However, a large proportion of chemical cross-linkers are more or less toxic and thus potentially dangerous in the field of tissue engineering. Gelatin scaffolds can also be cross-linked thermally [18], but adding cross-linking agents can enhance scaffold properties even further.