The growth inhibitory activity of
doxorubicin or cisplatin, as a single agent, may be
modified by combinations of P. emblica or T. bellerica
extracts and be synergistically enhanced in some cases.
Depending on the combination ratio, the doses for each
drug for a given degree of effect in the combination may
be reduced. The mechanisms involved in this interaction
between chemotherapeutic drugs and plant extracts
remain unclear and should be further evaluated.