The present investigation, aimed to identify the most appropriate leaching solvents mixture for pepper pigments to produce the best concentrated extract by examining the efficiency of different
solvents systems for the extraction both flavonoids and total phenolics in the pepper by-products and to evaluate the dyeing ability and potential antibacterial activity against some common human
pathogens; Staphylococcus aureus, and Pseudomonas aeruginosa as well as the antibacterial activities of wool fabrics.