Methods
In this report, we review the use of melatonin
for the treatment of a number of categories of
sleep disorders, including primary sleep disorders,
secondary sleep disorders, and sleep restriction, in
a number of different populations. Moreover, we
review not only the safety and effectiveness of
melatonin for the treatment of sleep disorders,
but also the pharmacology of exogenous
melatonin and the physiology of endogenous
melatonin, to provide a comprehensive overview
of the state of research in this area.