Systemic inflammation in people who are obese may lead to further health problems including diabetes and heart disease. Researchers studied mangosteen juice to see if it could lower signs of inflammation in obese volunteers. An article in "Nutrition Journal" reported that volunteers who drank mangosteen juice twice daily showed a significant reduction in inflammatory markers in their bloodstream, while markers for inflammation in a control group that received a different juice concoction didn't change. The authors cautioned that more studies are necessary to confirm the benefits of mangosteen juice and determine if there are any negative side effects.