hCG as a tumor marker however has a long serum half-life (two
compartment model, initial half-life approximately 15 h/late half-life
approximately 50 h depending on the variants of hCG detected by the
assay). In addition, hCG molecules in GTD are more heterogeneous
and degraded than in normal pregnancy [1,10–13].
In contrast hGH-V has a very short serum half-life of approximately
15min (two compartment model with an initial half-life of 5.8 min and
a late phase serum half-life depending on the body mass index) [