The accurate measurement of ultraviolet (UV) irradiation, especially within a container or vessel is one of the
challenges facing the broad implementation of UV sterilization. Currently, biological indicators are the best
method to determine whether an applied UV dose has the necessary efficacy to achieve sterilization. To overcome
some of the challenges of using a biological indicator, chemical indicators based upon the degradation
of food, drug and cosmetic (FD&C) dyes were developed. In this work, the relationship between UV dose and
dye degradation was elucidated and used to create standard curves which could be used as a quantitative
measurement system. The use of dye degradation as a measurement of UV dose is especially useful when
the levels of UV irradiation within a container cannot be measured directly. Additionally, due to the highly
colored nature of the FD&C dyes, the visual changes present upon dye irradiation can be used as a qualitative
visual indicator of the UV dose.
The accurate measurement of ultraviolet (UV) irradiation, especially within a container or vessel is one of the
challenges facing the broad implementation of UV sterilization. Currently, biological indicators are the best
method to determine whether an applied UV dose has the necessary efficacy to achieve sterilization. To overcome
some of the challenges of using a biological indicator, chemical indicators based upon the degradation
of food, drug and cosmetic (FD&C) dyes were developed. In this work, the relationship between UV dose and
dye degradation was elucidated and used to create standard curves which could be used as a quantitative
measurement system. The use of dye degradation as a measurement of UV dose is especially useful when
the levels of UV irradiation within a container cannot be measured directly. Additionally, due to the highly
colored nature of the FD&C dyes, the visual changes present upon dye irradiation can be used as a qualitative
visual indicator of the UV dose.
การแปล กรุณารอสักครู่..
