this study the antinociceptive, anti-inflammatory, antioxidant and antiulcer activity of ethanolic extract of Sterculia
scaphigera (EESS) was investigated. EESS (30,100, and 300 mg/kg) significantly inhibited acetic acid-induced writhing,
increased the reaction time to thermal stimulus in tail immersion test and inhibited paw licking in both neurogenic as well as
inflammatory phase in formalin induced paw licking test. EESS exhibited significant anti-inflammatory activity in carrageenan
induced paw edema in rats. The estimation of in-vivo antioxidant status in carrageenan paw edema showed that EESS
significantly increased the levels of SOD, catalase and GSH while levels of malondialdehyde were significantly decreased.
EESS also exhibited significant protection against formaldehyde induced arthritis in rats. SGOT and SGPT levels in aspirin and
EESS groups were also significantly decreased as compared to control in arthritis model. Significant cytoprotective effect of
EESS (100, 300 and 500 mg/kg) was observed in pyloric ligation and ethanol